Martina Rossi

PhD supervisor: Prof. Giuseppe Legname, Laboratory of Prion Biology

Summary of carrier/studies:

I approached to Neuroscience during my Bachelor internship at the Neuroscience Institute of the National Research Center (CNR), where I studied microvesicle release in response to microglia polarization. At the end of the course, I obtained a Bachelor’s Degree in Medical Biotechnology at the University of Milan. Then I attained a Master’s Degree in Molecular Biology at the same university. My Master thesis focused on the analysis of chemokine CCL2 and its receptor in the pathogenesis of a familial Amyotrophic Lateral Sclerosis (ALS) mouse model. During these initial research experiences, I discovered my interest in Neuroscience and, particularly, in Neurodegenerative Dementias. As life expectancy is raising and the risk of dementia increases with age, cognitive decline has emerged as one of the major health threats of our century. For this reason, my PhD project involves protein misfolding and aggregation studies, with particular focus on the detection of disease-specific biomarkers (eg. tau, α-synuclein and Aβ) in peripheral tissues of patients with different forms of Neurodegenerative Dementia.